Title: Prognosis of Rectal Cancer Patients Improves Analog to Downstaging by Intensified Neoadjuvant Radiochemotherapy -a Matched Pair Analysis
نویسندگان
چکیده
Leif Schiffmann ([email protected]) Gunther Klautke ([email protected]) Nicole Wedermann ([email protected]) Michael Gock ([email protected]) Friedrich Prall ([email protected]) Rainer Fietkau ([email protected]) Bettina M Rau ([email protected]) Ernst Klar ([email protected])
منابع مشابه
Intensified neoadjuvant radiochemotherapy for rectal cancer enhances surgical complications
BACKGROUND Neoadjuvant radiochemotherapy has proven superior to adjuvant treatment in reducing the rate of local recurrence without impairing cancer related survival or the incidence of distant metastases. The present study aimed at addressing the effects of an intensified protocol of neoadjuvant treatment on the development of postoperative complications. METHODS A total of 387 patients unde...
متن کاملAuthor's response to reviews Title: Intensified Neoadjuvant Radiochemotherapy for Rectal Cancer Enhances Surgical Complications Authors:
Leif Schiffmann ([email protected]) Nicole Wedermann ([email protected]) Michael Gock ([email protected]) Friedrich Prall ([email protected]) Gunther Klautke ([email protected]) Rainer Fietkau ([email protected]) Bettina Rau ([email protected]) Ernst Klar ([email protected]...
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Background: Purpose: The purpose of our study is to demonstrate that intensified neoadjuvant chemo-radiotherapy (CRT) treatment in locally advanced rectal cancer (LARC), aimed at further enhancing the complete pathological response and local disease control, is feasible and well tolerated. Materials and Methods: From January 2011 to December 2015, 62 patients (women 21, men 41, mean age 61,5, ...
متن کاملThe impact of preoperative radiochemotherapy on survival in advanced esophagogastric junction signet ring cell adenocarcinoma.
BACKGROUND Signet ring cell (SRC) tumors have a worse prognosis when compared with non-SRC tumors, and neoadjuvant chemotherapy has been suggested to be an ineffective treatment strategy. Preoperative radiochemotherapy, of already proven efficacy for esophagogastric junction adenocarcinomas (EGJA), could be an alternative neoadjuvant strategy for SRC EGJA. The aim of this retrospective study wa...
متن کاملسلکوکسیب همراه با کمورادیوتراپی نئوادجوانت در بیماران مبتلا به آدنوکارسینوم رکتوم مرحله II و III
Background: Colorectal cancer is the third common cancer world wide and the forth in Iran. Neoadjuvant chemoradiotherapy is the standard treatment for locally advanced rectal cancer. In this study we evaluate the efficacy a cox-2 inhibitor on pathologic response, sphincter preservation and acute toxicity during neoadjuvant chemoradiation. Methods: Thirty-six patients that have adenocarcinoma o...
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تاریخ انتشار 2012